News of how the National Heart & Lung Institute is being supported by the Foundation

Every year the Foundation funds up to six 3 or 4-year MRes/PhD Studentships
Recent Foundation students graduated with PhD doctrinal theses as follows:
  • Anna Cocking - Analysis of DDR1 (Discoidin Domain Receptor 1) function at epithelial cell contacts
  • Ann-Kathrin Reuschl - Primary human bronchial epithelial cells during tuberculosis infection
  • Fahima Kausar - The role of stromal cells during respiratory syncytial virus infection in vivo
  • Neil Saad - Influence of early life factors on later ventilatory function: interpreting associations with inflammation, cardiometabolic function and ethnicity
Other Research Postgraduate students who receive direct support from the Foundation recently gave presentations to Trustees on the following subjects:
“Pharmacological Mobilisation of Adult Stem/Progenitor Cells into the Circulation” 
“Investigating the effects of activated human neutrophils on airways”
"The regulation of new blood vessels through gene generation"
“Molecular Profiling of Cisplatin Resistance in Lung Cancer”
As a result of the Foundation's support NHLI is able to attract the most outstanding young scientists

The Foundation supports two senior members of the NHLI staff team:

Dr Sanjay Prasad, Consultant Cardiologist to (a) focus research into the risk of ventricular arrhythmia and heart failure (b) focus on early detection of patients with cardiomyopathy (c) help establish a unique large family clinic for screening and (d) help establish a large biobank which is assisting the work of the team’s genetic colleague.  Dr Prasad’s ongoing cardiology research includes looking at genetic profiles in patients with cardiomyopathy, and the development of greater understanding of aspects of dilated cardiomyopathy.

Prof Jadwiga (Wisia) Wedzicha, NHLI Clinical Chair in Respiratory Medicine, is overseeing a £2M Medical Research Council Partnership scheme, uniting eight hospitals/universities (coordinated by Imperial) to undertake COPD related research.  Chronic Obstructive Pulmonary Disease is the fourth most common cause of death worldwide.  Much research and scientific support to date has focused on alleviation of the effects of the disease.  This new Early COPD Partnership scheme aims to actively recruit, via GPs, a cohort of 1000 individuals aged in their 30s and 40s, who are smokers and therefore in the risk category for developing COPD in later life.  By gathering together data relating to all aspects of the health and lifestyle of this cohort it is expected that it will be possible to identify ways that COPD can be treated as early as possible.  The scheme has the support of several major pharmaceutical companies, and charities in addition to the NHLIF.  The links with Imperial are strong, with 2 PhD students being enabled to work within the scheme, along with 1 PhD student from each of the other 7 hospitals/universities.  Imperial’s Dept. of Computing is also to be involved, as they will oversee the management of the data relating to the cohort. 

Two NHLI Foundation Centres in Respiratory Medicine, one to be in Interstitial Lung Disease and the other in Respiratory Health, have been established in recognition of the very generous support that NHLI has received from the Foundation over time. 

For the latest published facts and figures about the National Heart & Lung Institute Foundation please click here
 
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